Comparison of FRAX and FRAX-TBS in predicting osteoprotic fracture risk in postmenopausal women

Frequency of FRAX risk factors in osteopenic postmenopausal women with and without history of fragility fracture.

OBJECTIVE Fractures associated with bone fragility represent a major public health concern. Although the risk of bone fracture is higher among patients with osteoporosis, the number of fractures is usually higher among patients with osteopenia due to its higher prevalence. METHODS This is an observational case series study that compares the frequencies of nonskeletal risk factors for osteopor...

Fracture risk prediction using BMD and clinical risk factors in early postmenopausal women: sensitivity of the WHO FRAX tool.

The aim of this prospective study was (1) to identify significant and independent clinical risk factors (CRFs) for major osteoporotic (OP) fracture among peri- and early postmenopausal women, (2) to assess, in this population, the discriminatory capacity of FRAX and bone mineral density (BMD) for the identification of women at high risk of fracture, and (3) to assess whether adding risk factors...

Frax score calculations in postmenopausal women with subclinical hypothyroidism.

OBJECTIVE The aim of our study was to evaluate the relationship between the elevated TSH and fracture risk in postmenopausal women with subclinical hypothyroidism for evaluation of individuals with a high risk for osteoporotic fractures. DESIGN FRAX score calculation (10-year estimated risk for bone fracture) and measurement of bone markers (osteocalcin and beta cross-laps) were performed in ...

Comparison of Stochastic Predictors and Trabecular Bone Score (TBS) in Predicting the Risk of Hip Fracture for Postmenopausal Women

Direct comparison of eight national FRAX® tools for fracture prediction and treatment qualification in Canadian women.

SUMMARY We compared the calibration of FRAX tools from Canada, the US (white), UK, Sweden, France, Australia, New Zealand, and China when used to assess fracture risk in 36,730 Canadian women. Our data underscores the importance of applying country-specific FRAX tools that are based upon high-quality national fracture epidemiology. PURPOSE A FRAX® model for Canada was constructed for predicti...